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KMID : 0903520070500030198
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2007 Volume.50 No. 3 p.198 ~ p.203
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Biological Activity of Omija (Schizandra chinensis Baillon) Extracts
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Cho Young-Je
Ju In-Sik
Kim Byung-Chul
Lee Woo-Shik
Kim Mi-Ja
Lee Byung-Gu
An Bong-Jeun
Kim Jeung-Hoan
Kwon O-Jun
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Abstract
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Extracts from Schizandra chinensis Baillon (Korean name: Omija) were tested for antioxidant and their inhibitory activities of α-amylase and α-glucosidase. Total contents of phenolics were found as 4.35 mg/g (water extract)~6.35 mg/g (60% ethanol extract). Electron donating ability (EDA), ABTS [2,2’-azinobis(3-ethyl-benzothiaznoline-6-sulfonic acid)] radical decolorization, antioxidant protection factor (PF) and thiobarbituric acid reactive substance (TBARS) were measured for the antioxidative activity of the extracts from S. chinensis. The water extract were determined as 97.5% at 200 μg/ml while the activity of 60% ethanol extract were 96.2% at 200 μg/ml in EDA. The 60% ethanol extract showed higher antioxidant activity than water extract when evaluated by ABTS radical decolorization, antioxidant PF and TBARS. α-Amylase inhibitory activity of water extract was similar with that of 60% EtOH extract. α-glucosidase inhibitory activities of water extract (97.4%) was higher than that of 60% ethanol extract (84.5%) at 200 μg/ml. The water extract from S. chinensis did not show an antimicrobial activity against Helicobacter pylori, but the 60% ethanol extract showed high antimicrobial activities such as 23 ± 1.6 mm of clear zone in 200 μg/ml of phenolics. The result suggest that the water and 60% ethanol extract from S. chinensis will be useful as natural antioxidants and functional foods.
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KEYWORD
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α-amylase, antimicrobial activity, α-glucosidase, Helicobacter pylori, Schizandra chinensis Baillon
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